Journal
JOURNAL OF CHILD NEUROLOGY
Volume 23, Issue 3, Pages 307-314Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0883073807308698
Keywords
autism spectrum disorder; metabolic diseases; behavioral phenotype
Categories
Ask authors/readers for more resources
Autism is an etiologic heterogeneous entity caused by many different diseases occurring in the central nervous system at an early stage in life. Several metabolic defects have been associated with autistic symptoms with a rate higher than that found in the general population. Inborn errors of metabolism can probably account for less than 5% of individuals. Selective metabolic testing should be done in the presence of suggestive clinical findings, including lethargy, cyclic vomiting, early seizures, dysmorphic features, and mental retardation. In some patients, early diagnosis of the metabolic disorders and proper therapeutic interventions may significantly improve the long-term cognitive and behavioral outcome.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available