Journal
JOURNAL OF CHEMICAL RESEARCH
Volume -, Issue 5, Pages 288-295Publisher
SCIENCE REVIEWS 2000 LTD
DOI: 10.3184/030823410X12746305905926
Keywords
amines; N-acetylation; chemoselectivity; metal acetates; metal oxides; acetic acid
Categories
Funding
- UGC, New Delhi
- Visva-Bharati University
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The use of catalytic amount of metal acetate or metal oxide in acetic acid is a new and highly efficient acetylating system for chemoselective N-acetylation of primary and secondary amines in excellent yields under reflux condition. No other solvent is required. The noted features of this method include mild reaction conditions, use of innocuous reagents, excellent yields, convenient work-up, and reuse of catalyst.
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