Related references
Note: Only part of the references are listed.Mechanisms of toxicity in C9FTLD/ALS
Tania F. Gendron et al.
ACTA NEUROPATHOLOGICA (2014)
Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis
Scott P. Allen et al.
NEUROBIOLOGY OF AGING (2014)
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
Sandra Almeida et al.
ACTA NEUROPATHOLOGICA (2013)
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?
Jessica L. Bell et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice
Erica D. Koval et al.
HUMAN MOLECULAR GENETICS (2013)
Hypolipidemia in Patients with Amyotrophic Lateral Sclerosis: A Possible Gender Difference?
Ji Won Yang et al.
JOURNAL OF CLINICAL NEUROLOGY (2013)
The common PARK8 mutation LRRK2 G2019S is not a risk factor for breast cancer in the absence of Parkinson's disease
H. Mortiboys et al.
JOURNAL OF NEUROLOGY (2013)
Analysis of hnRNPA1, A2/B1, and A3 genes in patients with amyotrophic lateral sclerosis
Daniela Calini et al.
NEUROBIOLOGY OF AGING (2013)
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
Shuo-Chien Ling et al.
NEURON (2013)
Systemic Down-Regulation of Delta-9 Desaturase Promotes Muscle Oxidative Metabolism and Accelerates Muscle Function Recovery following Nerve Injury
Ghulam Hussain et al.
PLOS ONE (2013)
The Omega-3 Fatty Acid Eicosapentaenoic Acid Accelerates Disease Progression in a Model of Amyotrophic Lateral Sclerosis
Ping K. Yip et al.
PLOS ONE (2013)
Nocturnal Hypoxia in ALS Is Related to Cognitive Dysfunction and Can Occur as Clusters of Desaturations
Su-Yeon Park et al.
PLOS ONE (2013)
Intermittent Hypoxia Can Aggravate Motor Neuronal Loss and Cognitive Dysfunction in ALS Mice
Sung-Min Kim et al.
PLOS ONE (2013)
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
Andrea Serio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Neuronal dark matter: the emerging role of microRNAs in neurodegeneration
Emily F. Goodall et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
High-caloric food supplements in the treatment of amyotrophic lateral sclerosis: A prospective interventional study
Johannes Dorst et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2013)
Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis
Axel Freischmidt et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2013)
Impaired response of hypoxic sensor protein HIF-1α and its downstream proteins in the spinal motor neurons of ALS model mice
Kota Sato et al.
BRAIN RESEARCH (2012)
Misregulated RNA processing in amyotrophic lateral sclerosis
Magdalini Polymenidou et al.
BRAIN RESEARCH (2012)
Iron Homeostasis Regulates the Activity of the MicroRNA Pathway through Poly(C)-Binding Protein 2
Yujing Li et al.
CELL METABOLISM (2012)
FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment
Mariangela Morlando et al.
EMBO JOURNAL (2012)
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
Julien Couthouis et al.
HUMAN MOLECULAR GENETICS (2012)
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
Oleg Butovsky et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
Elisa Majounie et al.
LANCET NEUROLOGY (2012)
Primary lateral sclerosis: Upper-motor-predominant amyotrophic lateral sclerosis with frontotemporal lobar degeneration - immunohistochemical and biochemical analyses of TDP-43
Takayuki Kosaka et al.
NEUROPATHOLOGY (2012)
TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
Yukio Kawahara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
Bilada Bilican et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
Naohiro Egawa et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Mutational Analysis Reveals the FUS Homolog TAF15 as a Candidate Gene for Familial Amyotrophic Lateral Sclerosis
N. Ticozzi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2011)
Amyotrophic Lateral Sclerosis Pathophysiology, Diagnosis and Management
Paul H. Gordon
CNS DRUGS (2011)
Hypoxia Inducible Factor-1 as a Target for Neurodegenerative Diseases
Z. Zhang et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Reduction in Expression of the Astrocyte Glutamate Transporter, GLT1, Worsens Functional and Histological Outcomes Following Traumatic Spinal Cord Injury
Angelo C. Lepore et al.
GLIA (2011)
Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
Miguel Mitne-Neto et al.
HUMAN MOLECULAR GENETICS (2011)
Patients with elevated triglyceride and cholesterol serum levels have a prolonged survival in amyotrophic lateral sclerosis
J. Dorst et al.
JOURNAL OF NEUROLOGY (2011)
Energy metabolism in amyotrophic lateral sclerosis
Luc Dupuis et al.
LANCET NEUROLOGY (2011)
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
Amanda M. Haidet-Phillips et al.
NATURE BIOTECHNOLOGY (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
DEREGULATION OF THE HYPOXIA INDUCIBLE FACTOR-1α PATHWAY IN MONOCYTES FROM SPORADIC AMYOTROPHIC LATERAL SCLEROSIS PATIENTS
C. Moreau et al.
NEUROSCIENCE (2011)
A decrease in body mass index is associated with faster progression of motor symptoms and shorter survival in ALS
Ali Jawaid et al.
AMYOTROPHIC LATERAL SCLEROSIS (2010)
Impaired glucose tolerance in patients with amyotrophic lateral sclerosis
Pierre-Francois Pradat et al.
AMYOTROPHIC LATERAL SCLEROSIS (2010)
An estimate of amyotrophic lateral sclerosis heritability using twin data
A. Al-Chalabi et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)
Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
Heather Mortiboys et al.
NEUROLOGY (2010)
The acute administration of eicosapentaenoic acid is neuroprotective after spinal cord compression injury in rats
Siew-Na Lim et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2010)
The Randle cycle revisited: a new head for an old hat
Louis Hue et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
MicroRNAs: Target Recognition and Regulatory Functions
David P. Bartel
CELL (2009)
HIF-1 alpha Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms
Alvaro Marin-Hernandez et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2009)
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
Michele Trabucchi et al.
NATURE (2009)
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
Da Wei Huang et al.
NATURE PROTOCOLS (2009)
Lower serum lipid levels are related to respiratory impairment in patients with ALS
A. Chio et al.
NEUROLOGY (2009)
MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice
Andrew H. Williams et al.
SCIENCE (2009)
The facilitative glucose transporter GLUT3: 20 years of distinction
Ian A. Simpson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Mitochondrial Function and Morphology Are Impaired in parkin-Mutant Fibroblasts
Heather Mortiboys et al.
ANNALS OF NEUROLOGY (2008)
Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
L. Dupuis et al.
NEUROLOGY (2008)
Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model
Jose-Luis Gonzalez de Aguilar et al.
PHYSIOLOGICAL GENOMICS (2008)
Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies
Ken Fujimura et al.
RNA (2008)
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
John T. Dimos et al.
SCIENCE (2008)
Diagnosis and management of motor neurone disease
Christopher J. McDermott et al.
BMJ-BRITISH MEDICAL JOURNAL (2008)
Clinical differentiation between primary lateral sclerosis and upper motor neuron predominant amyotrophic lateral sclerosis
Marc Gotkine et al.
ARCHIVES OF NEUROLOGY (2007)
Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS
Laura Ferraiuolo et al.
JOURNAL OF NEUROSCIENCE (2007)
Fatty acid transport protein 4 is the principal very long chain fatty Acyl-CoA synthetase in skin fibroblasts
Zhenzhen Jia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Cerebellar neuro degeneration in the absence of microRNAs
Anne Schaefer et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Argonaute proteins: Mediators of RNA silencing
Lasse Peters et al.
MOLECULAR CELL (2007)
Differentiation between primary lateral sclerosis and amyotrophic lateral sclerosis - Examination of symptoms and signs at disease onset and during follow-up
Maria Carmela Tartaglia et al.
ARCHIVES OF NEUROLOGY (2007)
Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat
VR King et al.
JOURNAL OF NEUROSCIENCE (2006)
A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis
Zhong Zhao et al.
BMC NEUROSCIENCE (2006)
ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis
MJ Greenway et al.
NATURE GENETICS (2006)
The natural history of primary lateral sclerosis
PH Gordon et al.
NEUROLOGY (2006)
Paradoxical response of VEGF expression to hypoxia in CSF of patients with ALS
C Moreau et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2006)
A unique gene expression signature discriminates familial Alzheimer's disease mutation carriers from their wild-type siblings
Y Nagasaka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells
N Scaglia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS
J Kirby et al.
BRAIN (2005)
Targeting Hypoxia-Inducible Factor (HIF) as a Therapeutic Strategy for CNS Disorders
Robert S. Freeman et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2005)
Normalization of real-time quantitative reverse transcription-PCR data: A model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets
CL Andersen et al.
CANCER RESEARCH (2004)
Evidence for defective energy homeostasis in amyotrophic lateral sclerosis:: benefit of a high-energy diet in a transgenic mouse
L Dupuis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The Microprocessor complex mediates the genesis of microRNAs
RI Gregory et al.
NATURE (2004)
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)
YZ Chen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Noninvasive ventilation in ALS - Indications and effect on quality of life
SC Bourke et al.
NEUROLOGY (2003)
Phosphotransfer networks and cellular energetics
PP Dzeja et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2003)
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
JM Ntambi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation
EC Lai
NATURE GENETICS (2002)
The effect of non-invasive positive pressure ventilation (NIPPV) on cognitive function in amyotrophic lateral sclerosis (ALS): a prospective study
IC Newsom-Davis et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2001)
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
B Oosthuyse et al.
NATURE GENETICS (2001)
Identification of WTAP, a novel Wilms' tumour 1-associating protein
NA Little et al.
HUMAN MOLECULAR GENETICS (2000)
Vascular endothelial growth factor:: Direct neuroprotective effect in in vitro ischemia
KL Jin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of γ-glutamylcysteine synthetase heavy subunit gene
J Jeyapaul et al.
BIOCHEMICAL PHARMACOLOGY (2000)