Journal
JOURNAL OF CHEMICAL PHYSICS
Volume 141, Issue 21, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.4903176
Keywords
-
Funding
- Academy of Finland through its COMP Center of Excellence Program [915804]
Ask authors/readers for more resources
We investigate the dynamics of pore-driven polymer translocation by theoretical analysis and molecular dynamics (MD) simulations. Using the tension propagation theory within the constant flux approximation we derive an explicit equation of motion for the tension front. From this we derive a scaling relation for the average translocation time tau, which captures the asymptotic result tau alpha N-0(1+nu), where N-0 is the chain length and nu is the Flory exponent. In addition, we derive the leading correction-to-scaling term to tau and show that all terms of order N-0(2 nu) exactly cancel out, leaving only a finite-chain length correction term due to the effective pore friction, which is linearly proportional to N-0. We use the model to numerically include fluctuations in the initial configuration of the polymer chain in addition to thermal noise. We show that when the cis side fluctuations are properly accounted for, the model not only reproduces previously known results but also considerably improves the estimates of the monomer waiting time distribution and the time evolution of the translocation coordinate s(t), showing excellent agreement with MD simulations. (C) 2014 AIP Publishing LLC.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available