Journal
NEURON
Volume 88, Issue 1, Pages 20-32Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2015.09.004
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Funding
- Israel Center for Research Excellence (I-CORE) Program of the Planning and Budgeting Committee
- Israel Science Foundation [51/11]
- Deutsche Forschungsgemeinschaft [SFB 654]
- Cognitive Architecture sub-project of the Human Brain Project of the European Community Seventh Framework Programme (FP7) [SP3]
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Memory consolidation refers to the transformation over time of experience-dependent internal representations and their neurobiological underpinnings. The process is assumed to be embodied in synaptic and cellular modifications at brain circuits in which the memory is initially encoded and to proceed by recurrent reactivations, both during wakefulness and during sleep, culminating in the distribution of information to additional locales and integration of new information into existing knowledge. We present snapshots of our current knowledge and gaps in knowledge concerning the progress of consolidation over time and the cognitive architecture that supports it and shapes our long-term memories.
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