4.7 Article

Original footage of the Chilean miners with manganism published in Neurology in 1967

Journal

NEUROLOGY
Volume 85, Issue 24, Pages 2166-2169

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.0000000000002223

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Manganism has captured the imagination of neurologists for more than a century because of its similarities to Parkinson disease and its indirect but seminal role in the l-dopa miracle. We present unpublished footage of the original case series reported in Neurology (R) in 1967 by Mena and Cotzias depicting the typical neurologic signs of manganism in 4 Chilean miners and their response to high doses of l-dopa.

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