4.7 Article

A practical, simple, and useful method of categorizing interictal EEG features in children

Journal

NEUROLOGY
Volume 85, Issue 5, Pages 471-478

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.0000000000001805

Keywords

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Funding

  1. Dravet Syndrome Foundation
  2. NIH/National Institute of Neurological Disorders and Stroke [1-RO1-NS43209]

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We introduce a simple scheme of categorizing interictal EEG in patients with pediatric epilepsy. Five patterns of EEG can be determined by using 2 interictal EEG domains: organization of the background activity and a morphology/topography of epileptiform discharges. These patterns relate to commonly recognized categories of pediatric epilepsy: familial epilepsies, genetic generalized epilepsies, self-limited epilepsies, epilepsies with encephalopathy, and focal structural epilepsies. Each group has distinguishable clinical presentations, inheritance patterns, and outcomes. This categorization may be a useful educational tool; it may also guide decisions about further testing and management.

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