4.7 Review

The decline and fall of the IGF-I receptor

Journal

JOURNAL OF CELLULAR PHYSIOLOGY
Volume 228, Issue 4, Pages 675-679

Publisher

WILEY
DOI: 10.1002/jcp.24217

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This review examines the effect of targeting the insulin-like growth factor 1 receptor (IGF-IR) in human cancers. The results are disappointing. The causes for the failure are discussed, as well as the possible use of the IGF-IR as a secondary target. J. Cell. Physiol. 228: 675679, 2013. (c) 2012 Wiley Periodicals, Inc.

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