Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume 218, Issue 2, Pages 251-255Publisher
WILEY
DOI: 10.1002/jcp.21607
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The unique properties of embryonic stem cells (ESCs) to self-renew indefinitely or to differentiate to any cell type have great potential for clinical applications in regenerative medicine. MicroRNAs (miRNAs) are emerging as important regulators of post-transcriptional gene expression and have been implicated as crucial elements in regulating ESCs. Here, we review recent progresses in characterizing the role of m RNAs in the maintenance and development of ESCs.
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