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Mechanisms of bone metastases of breast cancer
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NF-κB Activation, Dependent on Acetylation/Deacetylation, Contributes to HIF-1 Activity and Migration of Bone Metastatic Breast Carcinoma Cells
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MOLECULAR CANCER RESEARCH (2009)
Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells
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MOLECULAR CANCER THERAPEUTICS (2009)
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α
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PLOS ONE (2009)
Multiple Lineages of Human Breast Cancer Stem/Progenitor Cells Identified by Profiling with Stem Cell Markers
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PLOS ONE (2009)
Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations
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PLOS ONE (2009)
被撤回的出版物: Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells (Retracted article. See vol. 119, 2022)
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Synergic antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells
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BIOCHEMICAL PHARMACOLOGY (2008)
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Targeting cancer stem cells through L1CAM suppresses glioma growth
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CANCER RESEARCH (2008)
Potential for cripto-1 in defining stem cell-like characteristics in human malignant melanoma
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Role and regulation of prolyl hydroxylase domain proteins
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Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor
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Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer
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CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone
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Tumor environment dictates medulloblastoma cancer stem cell expression and invasive phenotype
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MOLECULAR CANCER RESEARCH (2008)
Identification of cells initiating human melanomas
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NATURE (2008)
Direct regulation of TWIST by HIF-1α promotes metastasis
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Antitumor activity of rapamycin in a phase I trial for patients with recurrent PTEN-Deficient glioblastoma
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Influence of oxygen tension on CD133 phenotype in human glioma cell cultures
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CANCER LETTERS (2007)
PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis
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CELLULAR SIGNALLING (2007)
Malignant astrocytic glioma: genetics, biology, and paths to treatment
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TGF-β and BMP7 interactions in tumour progression and bone metastasis
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CLINICAL & EXPERIMENTAL METASTASIS (2007)
Advances in counselling and surveillance patients at risk for pancreatic cancer
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GUT (2007)
Hypoxia enhances metastatic efficiency in HT1080 fibrosarcorna cells by increasing cell survival in lungs, not cell adhesion and invasion
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Current concepts: Local therapy and survival in breast cancer
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NEW ENGLAND JOURNAL OF MEDICINE (2007)
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HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity
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Mutant V600E BRAF increases hypoxia inducible factor-1α expression in melanoma
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CANCER CELL (2007)
Serum macrophage inhibitory cytokine-1 concentrations correlate with the presence of prostate cancer bone metastases
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Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia
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Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential
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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
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Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
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Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma:: HIF-2α promotes an aggressive phenotype
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Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
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Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
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Adding chloroquine to conventional treatment for glioblastoma multiforme -: A randomized, double-blind, placebo-controlled trial
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HIF-2α regulates Oct-4:: effects of hypoxia on stem cell function, embryonic development, and tumor growth
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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment
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BLOOD (2006)
Small interfering RNA expression vector targeting hypoxia-inducible factor 1 alpha inhibits tumor growth in hepatobiliary and pancreatic cancers
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MITF: master regulator of melanocyte development and melanoma oncogene
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CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: The role of bone microenvironment-associated CXCL12
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Recent advances on the molecular mechanisms involved in pancreatic cancer progression and therapies
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PANCREAS (2005)
A tumorigenic subpopulation with stem cell properties in melanomas
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CANCER RESEARCH (2005)
Cripto-1: A multifunctional modulator during embryogenesis and oncogenesis
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Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
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ONCOGENE (2005)
Hypoxia-inducible factor 1α is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells
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Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1α
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
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NEW ENGLAND JOURNAL OF MEDICINE (2005)
Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo
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The mammalian basic helix-loop-helix/PAS family of transcriptional regulators
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The von Hippel-Lindau tumor suppressor gene and kidney cancer
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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
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NEW ENGLAND JOURNAL OF MEDICINE (2004)
Fatty acid synthase: A metabolic oncogene in prostate cancer?
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NEW ENGLAND JOURNAL OF MEDICINE (2004)
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NEW ENGLAND JOURNAL OF MEDICINE (2004)
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: Role of reoxygenation, free radicals, and stress granules
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CANCER CELL (2004)
Hypoxia-inducible factors 1α and 2α are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin
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MELANOMA RESEARCH (2003)
Regulation of hypoxia-inducible factor-1α, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer
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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
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CANCER (2003)
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells
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MOLECULAR AND CELLULAR BIOLOGY (2000)
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