4.5 Review

Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis

Related references

Note: Only part of the references are listed.
Review Neurosciences

APP processing in Alzheimer's disease

Yun-Wu Zhang et al.

MOLECULAR BRAIN (2011)

Article Biochemistry & Molecular Biology

GRK5 Deficiency Accelerates β-Amyloid Accumulation in Tg2576 Mice via Impaired Cholinergic Activity

Shaowu Cheng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Clinical Neurology

Effects of insulinic therapy on cognitive impairment in patients with Alzheimer disease and Diabetes Mellitus type-2

Massimiliano Plastino et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2010)

Editorial Material Multidisciplinary Sciences

Linking type 2 diabetes and Alzheimer's disease

Weiping Han et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

RAGE regulates BACE1 and Aβ generation via NFAT1 activation in Alzheimer's disease animal model

H. J. Cho et al.

FASEB JOURNAL (2009)

Article Multidisciplinary Sciences

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

Fernanda G. De Felice et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Pharmacology & Pharmacy

Peripheral elevation of IGF-1 fails to alter Aβ clearance in multiple in vivo models

Thomas A. Lanz et al.

BIOCHEMICAL PHARMACOLOGY (2008)

Article Neurosciences

β-amyloid1-42 induces neuronal death through the p75 neurotrophin receptor

Areechun Sotthibundhu et al.

JOURNAL OF NEUROSCIENCE (2008)

Review Geriatrics & Gerontology

Aging of the brain, neurotrophin signaling, and Alzheimer's disease: Is IGF1-R the common culprit?

Luigi Puglielli

NEUROBIOLOGY OF AGING (2008)

Article Geriatrics & Gerontology

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

Fernanda G. De Felice et al.

NEUROBIOLOGY OF AGING (2008)

Article Multidisciplinary Sciences

Functionally significant insulin-like growth factor I receptor mutations in centenarians

Yousin Suh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Cell Biology

Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology

R. Liu et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)

Review Neurosciences

Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms

Emmanuel Planel et al.

JOURNAL OF NEUROSCIENCE (2007)

Review Pharmacology & Pharmacy

Targeting insulin-like growth factor-1 to treat Alzheimer's disease

Ignacio Torres-Aleman

EXPERT OPINION ON THERAPEUTIC TARGETS (2007)

Article Biochemistry & Molecular Biology

IGF-1-induced processing of the amyloid precursor protein family is mediated by different signaling pathways

Linda Adlerz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Cell Biology

Soluble protein oligomers in neurodegeneration:: lessons from the Alzheimer's amyloid β-peptide

Christian Haass et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

Opposing activities protect against age-onset proteotoxicity

Ehud Cohen et al.

SCIENCE (2006)

Article Endocrinology & Metabolism

Endocrine, liver-derived IGF-I is of importance for spatial learning and memory in old mice

J. Svensson et al.

JOURNAL OF ENDOCRINOLOGY (2006)

Article Biochemistry & Molecular Biology

An aging pathway controls the TrkA to p75NTR receptor switch and amyloid β-peptide generation

Claudio Costantini et al.

EMBO JOURNAL (2006)

Article Endocrinology & Metabolism

Peripheral hyperinsulinemia promotes tau phosphorylation in vivo

S Freude et al.

DIABETES (2005)

Article Endocrinology & Metabolism

Tau is hyperphosphorylated in the insulin-like growth factor-I null brain

CM Cheng et al.

ENDOCRINOLOGY (2005)

Review Geriatrics & Gerontology

Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease

GK Gouras et al.

NEUROBIOLOGY OF AGING (2005)

Article Geriatrics & Gerontology

Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice

LY Sun et al.

NEUROBIOLOGY OF AGING (2005)

Article Biochemistry & Molecular Biology

A biochemical and functional characterization of diet-induced brain insulin resistance

JG Mielke et al.

JOURNAL OF NEUROCHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective

RE Tanzi et al.

Review Clinical Neurology

Midlife cardiovascular risk factors and risk of dementia in late life

RA Whitmer et al.

NEUROLOGY (2005)

Review Biochemistry & Molecular Biology

Tau pathology in Alzheimer disease and other tauopathies

K Iqbal et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Article Pharmacology & Pharmacy

The source of cerebral insulin

WA Banks

EUROPEAN JOURNAL OF PHARMACOLOGY (2004)

Article Pharmacology & Pharmacy

Signaling by insulin-like growth factor 1 in brain

CA Bondy et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2004)

Article Multidisciplinary Sciences

Role for neuronal insulin resistance in neurodegenerative diseases

M Schubert et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Endocrinology & Metabolism

Insulin stimulates interleukin-6 and tumor necrosis factor-α gene expression in human subcutaneous adipose tissue

R Krogh-Madsen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Endocrinology & Metabolism

Increased risk of type 2 diabetes in Alzheimer disease

J Janson et al.

DIABETES (2004)

Article Clinical Neurology

Hyperinsulinemia and risk of Alzheimer disease

JA Luchsinger et al.

NEUROLOGY (2004)

Article Endocrinology & Metabolism

Role of insulin-like growth factor I in maintaining normal glucose homeostasis

DR Clemmons

HORMONE RESEARCH (2004)

Article Endocrinology & Metabolism

Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI

T den Heijer et al.

DIABETOLOGIA (2003)

Review Geriatrics & Gerontology

Diabetes, Alzheimer's disease and apolipoprotein genotype

C Messier

EXPERIMENTAL GERONTOLOGY (2003)

Review Biochemistry & Molecular Biology

Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling

AM Johnston et al.

FEBS LETTERS (2003)

Article Geriatrics & Gerontology

Insulin-like growth factor I (IGF-I) and cognitive decline in older persons

MG Dik et al.

NEUROBIOLOGY OF AGING (2003)

Article Biochemistry & Molecular Biology

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

R Deane et al.

NATURE MEDICINE (2003)

Article Multidisciplinary Sciences

γ-secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

WT Kimberly et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Neurosciences

APP processing and synaptic function

F Kamenetz et al.

NEURON (2003)

Article Endocrinology & Metabolism

Soluble tumor necrosis Factor-α receptors in young obese subjects with normal and impaired glucose tolerance

S Dzienis-Straczkowska et al.

DIABETES CARE (2003)

Article Biochemistry & Molecular Biology

The induction of the TNFα death domain signaling pathway in Alzheimer's disease brain

M Zhao et al.

NEUROCHEMICAL RESEARCH (2003)

Article Geriatrics & Gerontology

Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses

EM Mandelkow et al.

NEUROBIOLOGY OF AGING (2003)

Review Pharmacology & Pharmacy

Insulin and the blood-brain barrier

SC Woods et al.

CURRENT PHARMACEUTICAL DESIGN (2003)

Review Neurosciences

Alzheimer's disease: treatments in discovery and development

M Citron

NATURE NEUROSCIENCE (2002)

Review Biochemistry & Molecular Biology

The role of mitogen-activated protein kinase pathways in Alzheimer's disease

XW Zhu et al.

NEUROSIGNALS (2002)

Article Endocrinology & Metabolism

Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans

M Soop et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)

Article Clinical Neurology

Increased expression of the amyloid precursor β-secretase in Alzheimer's disease

RMD Holsinger et al.

ANNALS OF NEUROLOGY (2002)

Article Multidisciplinary Sciences

Ablation of insulin-producing neurons in flies: Growth and diabetic phenotypes

EJ Rulifson et al.

SCIENCE (2002)

Article Biochemistry & Molecular Biology

Hydrogen peroxide-mediated phosphorylation of ERK1/2, Akt/PKB and JNK in cortical neurones: dependence on Ca2+ and PI3-kinase

AJ Crossthwaite et al.

JOURNAL OF NEUROCHEMISTRY (2002)

Article Geriatrics & Gerontology

Genetics of interleukin 6: implications for Alzheimer's disease

A Papassotiropoulos et al.

NEUROBIOLOGY OF AGING (2001)

Article Geriatrics & Gerontology

Interleukin-1, neuroinflammation, and Alzheimer's disease

RE Mrak et al.

NEUROBIOLOGY OF AGING (2001)

Article Clinical Neurology

Oxidative damage is the earliest event in Alzheimer disease

A Nunomura et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)

Article Multidisciplinary Sciences

Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis

VA Skeberdis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Multidisciplinary Sciences

Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats

LP Reagan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Neurosciences

Neurodegenerative tauopathies

VMY Lee et al.

ANNUAL REVIEW OF NEUROSCIENCE (2001)

Review Behavioral Sciences

Insulin receptors and insulin action in the brain: review and clinical implications

RJ Schulingkamp et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2000)

Article Endocrinology & Metabolism

Variations in plasma soluble tumour necrosis factor receptors after diet-induced weight loss in obesity

JP Bastard et al.

DIABETES OBESITY & METABOLISM (2000)

Review Geriatrics & Gerontology

Inflammation and Alzheimer's disease

H Akiyama et al.

NEUROBIOLOGY OF AGING (2000)