4.5 Review

Engineering skeletal muscle tissue - new perspectives in vitro and in vivo

Journal

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Volume 14, Issue 11, Pages 2622-2629

Publisher

WILEY
DOI: 10.1111/j.1582-4934.2010.01183.x

Keywords

skeletal muscle tissue engineering; satellite cells; electrospun nanofibre matrices; nanotechnology

Funding

  1. University of Erlangen
  2. 'Xue Hong und Hans Georg Geis Foundation

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Muscle tissue engineering (TE) has not yet been clinically applied because of several problems. However, the field of skeletal muscle TE has been developing tremendously and new approaches and techniques have emerged. This review will highlight recent developments in the field of nanotechnology, especially electrospun nanofibre matrices, as well as potential cell sources for muscle TE. Important developments in cardiac muscle TE and clinical studies on Duchenne muscular dystrophy (DMD) will be included to show their implications on skeletal muscle TE.

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