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Mutation studies in CD3(+), CD19(+) and CD34(+) cell fractions in myeloproliferative disorders with homozygous JAK2(V617F) in granulocytes
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RA Van Etten
LEUKEMIA RESEARCH (2004)
Molecular and cytogenetic characterization of a novel translocation t(4;22) involving the breakpoint cluster region and platelet-derived growth factor receptor-alpha genes in a patient with atypical chronic myeloid leukemia
AM Safley et al.
GENES CHROMOSOMES & CANCER (2004)
Chronic myeloproliferative disorders with rearrangement of the platelet-derived growth factor α receptor:: a new clinical target for STI571/Glivec
P Trempat et al.
ONCOGENE (2003)
Imatinib for systemic mast-cell disease
A Pardanani et al.
LANCET (2003)
Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit
C Akin et al.
EXPERIMENTAL HEMATOLOGY (2003)
Clinical and genetic studies of ETV6/ABL1-positive chronic myeloid leukaemia in blast crisis treated with imatinib mesylate
A Barbouti et al.
BRITISH JOURNAL OF HAEMATOLOGY (2003)
Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome
JH Griffin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver
PT Ferrao et al.
LEUKEMIA RESEARCH (2003)
Imatinib therapy for hypereosinophilic syndrome and other eosinophilic disorders
A Pardanani et al.
BLOOD (2003)
PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease
J Cools et al.
CANCER CELL (2003)
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
J Cools et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms
Y Zermati et al.
ONCOGENE (2003)
Endogenous retroviral sequence is fused to FGFR1 kinase in the 8p12 stem-cell myeloproliferative disorder with t(8;19)(p12;q13.3)
G Guasch et al.
BLOOD (2003)
Cloning of the t(l;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib
K Wilkinson et al.
BLOOD (2003)
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy
A Pardanani et al.
BLOOD (2003)
Identification of an ETV6-ABL2 fusion transcript in combination with an ETV6 point mutation in a T-cell acute lymphoblastic leukaemia cell line
F Griesinger et al.
BRITISH JOURNAL OF HAEMATOLOGY (2002)
Chronic myelocytic leukemia with eosinophilia, t(9;12)(q34;p13), and ETV6-ABL gene rearrangement: case report and review of the literature
YK Keung et al.
CANCER GENETICS AND CYTOGENETICS (2002)
A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
OG Ottmann et al.
BLOOD (2002)
Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
JF Apperley et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
GD Demetri et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Evidence for the involvement of a hematopoietic progenitor cell in systemic mastocytosis from single-cell analysis of mutations in the c-kit gene
AS Yavuz et al.
BLOOD (2002)
The Tel-Abl (ETV6-Abl) tyrosine kinase, product of complex (9;12) translocations in human leukemia, induces distinct myeloproliferative disease in mice
RP Million et al.
BLOOD (2002)
The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA
EJ Baxter et al.
HUMAN MOLECULAR GENETICS (2002)
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study
CL Sawyers et al.
BLOOD (2002)
Imatinib mesylate (ST1571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase
HM Kantarjian et al.
BLOOD (2002)
Treatment of hypereosinophilic syndrome with imatinib mesilate
GJ Gleich et al.
LANCET (2002)
Transient response to imatinib mesylate (STI571) in a patient with the ETV6-ABL t(9;12) translocation
SG O'Brien et al.
BLOOD (2002)
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study
M Talpaz et al.
BLOOD (2002)
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia.
H Kantarjian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins
A Demiroglu et al.
BLOOD (2001)
8p12 stem cell myeloproliferative disorder:: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways
G Guasch et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder:: The first fusion gene involving BCR but not ABL
T Fioretos et al.
GENES CHROMOSOMES & CANCER (2001)
Safety and efficacy of imatinib (ST1571) in metastatic gastrointestinal stromal tumours: a phase I study
AT van Oosterom et al.
LANCET (2001)
Rabaptin-5 is a novel fusion partner to platelet-derived growth factor β receptor in chronic myelomonocytic leukemia
MK Magnusson et al.
BLOOD (2001)
Identification of four new translocations involving FGFRI in myeloid disorders
J Sohal et al.
GENES CHROMOSOMES & CANCER (2001)
The Kit-activating mutation D816V enhances stem cell factor-dependent chemotaxis
ML Taylor et al.
BLOOD (2001)
H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22)
J Schwaller et al.
BLOOD (2001)
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
BJ Druker et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the philadelphia chromosome.
BJ Druker et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia
M Ballmaier et al.
BLOOD (2001)
The 8p12 myeloproliferative disorder. t(8;19)(p12;q13.3):: a novel translocation involving the FGFR1 gene
F Mugneret et al.
BRITISH JOURNAL OF HAEMATOLOGY (2000)
Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase
T Schindler et al.
SCIENCE (2000)
Analysis of the surface expression of c-kit and occurrence of the c-kit Asp816Val activating mutation in T cells, B cells, and myelomonocytic cells in patients with mastocytosis
C Akin et al.
EXPERIMENTAL HEMATOLOGY (2000)