Related references
Note: Only part of the references are listed.RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
Y. Dondelinger et al.
CELL DEATH AND DIFFERENTIATION (2013)
TAK1 Is Essential for Osteoclast Differentiation and Is an Important Modulator of Cell Death by Apoptosis and Necroptosis
Betty Lamothe et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
RIP3 Inhibits Inflammatory Hepatocarcinogenesis but Promotes Cholestasis by Controlling Caspase-8-and JNK-Dependent Compensatory Cell Proliferation
Mihael Vucur et al.
CELL REPORTS (2013)
TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration
Sho Morioka et al.
BLOOD (2012)
Many stimuli pull the necrotic trigger, an overview
N. Vanlangenakker et al.
CELL DEATH AND DIFFERENTIATION (2012)
The flick of a switch: which death program to choose?
P. Vandenabeele et al.
CELL DEATH AND DIFFERENTIATION (2012)
TAK1 (MAP3K7) Signaling Regulates Hematopoietic Stem Cells through TNF-Dependent and -Independent Mechanisms
Giichi Takaesu et al.
PLOS ONE (2012)
Survival Function of the FADD-CASPASE-8-cFLIPL Complex
Christopher P. Dillon et al.
CELL REPORTS (2012)
TNF-α/Fas-RIP-1-induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations
Yechen Xiao et al.
BLOOD (2011)
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
N. Vanlangenakker et al.
CELL DEATH AND DIFFERENTIATION (2011)
RIPK-Dependent Necrosis and Its Regulation by Caspases: A Mystery in Five Acts
Douglas R. Green et al.
MOLECULAR CELL (2011)
cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
Maria Feoktistova et al.
MOLECULAR CELL (2011)
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
Tencho Tenev et al.
MOLECULAR CELL (2011)
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
Patrick-Simon Welz et al.
NATURE (2011)
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
Claudia Guenther et al.
NATURE (2011)
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
William J. Kaiser et al.
NATURE (2011)
Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis
Andrew Oberst et al.
NATURE (2011)
Functional complementation between FADD and RIP1 in embryos and lymphocytes
Haibing Zhang et al.
NATURE (2011)
Caspase 8 inhibits programmed necrosis by processing CYLD
Marie Anne O'Donnell et al.
NATURE CELL BIOLOGY (2011)
Programmed necrosis: backup to and competitor with apoptosis in the immune system
Jiahuai Han et al.
NATURE IMMUNOLOGY (2011)
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival
Andrew Oberst et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
The Prevalence of TNFα-Induced Necrosis over Apoptosis Is Determined by TAK1-RIP1 Interplay
Seda Coel Arslan et al.
PLOS ONE (2011)
TAK1 Suppresses a NEMO-Dependent but NF-κB-Independent Pathway to Liver Cancer
Kira Bettermann et al.
CANCER CELL (2010)
Alternative cell death mechanisms in development and beyond
Junying Yuan et al.
GENES & DEVELOPMENT (2010)
Transforming Growth Factor β-activated Kinase 1 (TAK1) Kinase Adaptor, TAK1-binding Protein 2, Plays Dual Roles in TAK1 Signaling by Recruiting Both an Activator and an Inhibitor of TAK1 Kinase in Tumor Necrosis Factor Signaling Pathway
Peter Broglie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Molecular mechanisms of necroptosis: an ordered cellular explosion
Peter Vandenabeele et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis
Sayaka Inokuchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
YoungSik Cho et al.
CELL (2009)
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
Sudan He et al.
CELL (2009)
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
Andrew Kovalenko et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP
S. Morioka et al.
ONCOGENE (2009)
Regulation of tissue homeostasis by NF-κB signalling: implications for inflammatory diseases
Manolis Pasparakis
NATURE REVIEWS IMMUNOLOGY (2009)
TNF-α induces two distinct caspase-8 activation pathways
Lai Wang et al.
CELL (2008)
Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
Junichi Hitomi et al.
CELL (2008)
Shared principles in NF-κB signaling
Matthew S. Hayden et al.
CELL (2008)
Protein phosphatase 2A is a negative regulator of transforming growth factor-β1-induced TAK1 activation in mesangial cells
Sung Il Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TAK1-binding Protein 1, TAB1, Mediates Osmotic Stress-induced TAK1 Activation but Is Dispensable for TAK1-mediated Cytokine Signaling
Maiko Inagaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity
Emily Omori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis
Rie Kajino-Sakamoto et al.
JOURNAL OF IMMUNOLOGY (2008)
Identification of RIP1 kinase as a specific cellular target of necrostatins
Alexei Degterev et al.
NATURE CHEMICAL BIOLOGY (2008)
Ubiquitination of RIP1 regulates an NF-κB independent cell-death switch in TNF signaling
Marie Anne O'Donnell et al.
CURRENT BIOLOGY (2007)
Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway
Taisuke Kajino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis
Emily Omori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
JH Shim et al.
GENES & DEVELOPMENT (2005)
Essential function for the kinase TAK1 in innate and adaptive immune responses
S Sato et al.
NATURE IMMUNOLOGY (2005)
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
A Degterev et al.
NATURE CHEMICAL BIOLOGY (2005)
Kinase RIP3 is dispensable for normal NF-KBs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and toll-like receptors 2 and 4
K Newton et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death
L Li et al.
SCIENCE (2004)
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
O Micheau et al.
CELL (2003)
TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling
H Sanjo et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Plat-E: an efficient and stable system for transient packaging of retroviruses
S Morita et al.
GENE THERAPY (2000)
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
G Takaesu et al.
MOLECULAR CELL (2000)
TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
K Kishimoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)