Journal
JOURNAL OF CELL BIOLOGY
Volume 204, Issue 2, Pages 153-163Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201310135
Keywords
-
Categories
Funding
- Israel Science Foundation [269/12]
Ask authors/readers for more resources
Pluripotent stem cells (PSCs) must maintain their proper genomic content in order to preserve appropriate self-renewal and differentiation capacities. However, their prolonged in vitro propagation, as well as the environmental culture conditions, present serious challenges to genome maintenance. Recent work has been focused on potential means to alleviate the genomic insults experienced by PSCs, and to detect them as soon as they arise, in order to prevent the detrimental consequences of these genomic aberrations on PSC application in basic research and regenerative medicine.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available