Journal
JOURNAL OF CELL BIOLOGY
Volume 190, Issue 1, Pages 9-20Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201001138
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Funding
- NIDCD [DC007704, DC005965]
- NIDCD Division of Intramural Research
- Skaggs Institute for Chemical Biology
- Dorris Neuroscience Center
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Mammals have an astonishing ability to sense and discriminate sounds of different frequencies and intensities. Fundamental for this process are mechanosensory hair cells in the inner ear that convert sound-induced vibrations into electrical signals. The study of genes that are linked to deafness has provided insights into the cell biological mechanisms that control hair cell development and their function as mechanosensors.
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