Related references
Note: Only part of the references are listed.Aging and disease: connections to sirtuins
Gizem Donmez et al.
AGING CELL (2010)
Inhibition of Nicotinamide Phosphoribosyltransferase CELLULAR BIOENERGETICS REVEALS A MITOCHONDRIAL INSENSITIVE NAD POOL
Maria Pittelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
Michelle Pacholec et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats
Erika Koltai et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2010)
SIRT1 is regulated by a PPARγ-SIRT1 negative feedback loop associated with senescence
Limin Han et al.
NUCLEIC ACIDS RESEARCH (2010)
A possibility of nutriceuticals as an anti-aging intervention: Activation of sirtuins by promoting mammalian NAD biosynthesis
Shin-ichiro Imai
PHARMACOLOGICAL RESEARCH (2010)
Photoprotective effects of nicotinamide
Diona L. Damian
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2010)
Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection
Kenichi Kakefuda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies
Aimable Nahimana et al.
BLOOD (2009)
Niacin: a re-emerging pharmaceutical for the treatment of dyslipidaemia
Helen Vosper
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice
Kathryn Moynihan Ramsey et al.
AGING CELL (2008)
Nicotinic acid nicotinamide and nicotinamide riboside: A molecular evaluation of NAD(+) precursor vitamins in human nutrition
Katrina L. Bogan et al.
ANNUAL REVIEW OF NUTRITION (2008)
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
Fabio Malavasi et al.
PHYSIOLOGICAL REVIEWS (2008)
The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor
Kyle Holen et al.
INVESTIGATIONAL NEW DRUGS (2008)
Human mesenchymal stem cells: from basic biology to clinical applications
B. M. Abdallah et al.
GENE THERAPY (2008)
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
Joseph T. Rodgers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Sirt1 regulates aging and resistance to oxidative stress in the heart
Ralph R. Alcendor et al.
CIRCULATION RESEARCH (2007)
NAD+ metabolism in health and disease
Peter Belenky et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Progressive loss of SIRT1 with cell cycle withdrawal
Tsutomu Sasaki et al.
AGING CELL (2006)
Poly(ADP-ribose):: novel functions for an old molecule
Valerie Schreiber et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells
CM Bäckesjö et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2006)
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage
JM Solomon et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Calorie restriction, SIRT1 and metabolism: Understanding longevity
L Bordone et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins
M Di Girolamo et al.
FEBS JOURNAL (2005)
Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor I/insulin signaling and caloric restriction
KA Al-Regaiey et al.
ENDOCRINOLOGY (2005)
The new life of a centenarian:: signalling functions of NAD(P)
F Berger et al.
TRENDS IN BIOCHEMICAL SCIENCES (2004)
PPARγ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
T Akune et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Enhanced bone formation in lipodystrophic PPARγhyp/hyp mice relocates haematopoiesis to the spleen
TA Cock et al.
EMBO REPORTS (2004)
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
JG Wood et al.
NATURE (2004)
Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases
MT Borra et al.
BIOCHEMISTRY (2004)
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
S Nemoto et al.
SCIENCE (2004)
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen et al.
SCIENCE (2004)
Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells:: the role of PPAR-γ2 transcription factor and TGF-β/BMP signaling pathways
EJ Moerman et al.
AGING CELL (2004)
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
B Rogina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
F Picard et al.
NATURE (2004)
The Sir2 family of protein deacetylases
G Blander et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases
MD Jackson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry
AA Sauve et al.
BIOCHEMISTRY (2003)
PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy?
TM Larsen et al.
INTERNATIONAL JOURNAL OF OBESITY (2003)
Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction
B Rogina et al.
SCIENCE (2002)
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
KJ Bitterman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Tetracycline and Niacinamide in the treatment of blistering skin diseases
GC Chaidemenos
CLINICS IN DERMATOLOGY (2001)
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
HA Tissenbaum et al.
NATURE (2001)
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product
JC Tanny et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
J Justesen et al.
BIOGERONTOLOGY (2001)
Role of NAD+ in the deacetylase activity of the SIR2-like proteins
J Landry et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Multilineage differentiation of Cbfa1-deficient calvarial cells in vitro
H Kobayashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)