Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 25, Issue 4, Pages 858-865Publisher
WILEY-BLACKWELL
DOI: 10.1359/jbmr.091012
Keywords
OSTEOARTHRITIS; BONE LOSS; KNEE; HIP; OLDER ADULTS
Categories
Funding
- National Health and Medical Research Council of Australia
- Arthritis Foundation of Australia
- Tasmanian Community Fund
- University of Tasmania
Ask authors/readers for more resources
The relationship between osteoarthritis (OA) and osteoporosis remains controversial This study was designed to determine the association between hip and knee radiographic OA and change in total hip bone mineral density (BMD) over 2 6 years A total of 867 population-based randomly selected subjects (mean age 62 years, range 51 to 80 years, and 49% female) were included Hip and knee joint space narrowing (JSN, 0 to 3) and osteophytes (0 to 3) in both lower limbs was assessed using Altman's atlas Total hip BMD was measured by dual-energy X-ray absorptiometry (DXA). We found that radiographic OA (score of JSN or osteophytes > 0) was common in this sample (hip 45%, knee 68%). In multivanable analyses, percentage change in total hip BMD per year was predicted by right and left hip axial (beta - -0.25% and -0.29% per grade, respectively, both p < .05), right hip superior femoral osteophytes (grades 2 and 3 versus 0 beta - -1 60, p < 05), combined right and left knee tibiofemoral JSN (beta = -006 per grade from grades 0 to 12, p < 05), and osteophytes (beta = -0 06 per grade from grades 0 to 14, p < 05) independent of each other and joint pain In conclusion, older subjects with radiographic hip and knee OA have higher total hip bone loss over 2.6 years regardless of symptoms, suggesting that consideration should be given to the monitoring of bone mass in these subjects. (C) 2010 American Society for Bone and Mineral Research.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available