4.4 Article

Decreased hydrogen production leads to selective butanol production in co-cultures of Clostridium thermocellum and Clostridium saccharoperbutylacetonicum strain N1-4

Journal

JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 115, Issue 2, Pages 173-175

Publisher

SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/j.jbiosc.2012.08.020

Keywords

Butanol production; Hydrogen production; Clostridium species; Hydrogenase; Co-culture

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When Clostridium thermocellum and Clostridium saccharoperbutylacetonicum strain N1-4 were co-cultured hydrogen production decreased and butanol was selectively produced with extremely low level of acetone. Since the high butanol production correlates with low hydrogen production, the molecular selection of hydrogenase gene activity is expected to yield strains exhibiting a higher butanol ratio. (C) 2012, The Society for Biotechnology, Japan. All rights reserved.

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