Journal
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 113, Issue 2, Pages 192-195Publisher
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/j.jbiosc.2011.09.019
Keywords
Saccharomyces cerevisiae; Ethanol production; Alcohol dehydrogenase isozymes; Gene disruption; Continuous culture
Funding
- Ministry of Education, Culture, Sports, Science, and Technology, Japan
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We analyzed the effects of the deletions of genes encoding alcohol dehydrogenase (ADH) isozymes of Saccharomyces cerevisiae. The decrease in ethanol production by ADH1 deletion alone could be partially compensated by the upregulation of other isozyme genes, while the deletion of all known ADH isozyme genes stably disrupted ethanol production. (C) 2011, The Society for Biotechnology, Japan. All rights reserved.
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