4.4 Article

Personalized assessment of oxidative cellular damages associated with diabetes using erythrocytes adhesion assay

Journal

JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 112, Issue 6, Pages 635-637

Publisher

SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/j.jbiosc.2011.08.003

Keywords

Erythrocytes; Diabetes; Oxidative stress; Cell adhesion; HbA(1c)

Funding

  1. Ministry of Education, Sports, Science and Technology, Japan [21656214]
  2. Funding Program for Next Generation World-Leading Researchers (NEXT Program) [LR016]
  3. Grants-in-Aid for Scientific Research [21656214] Funding Source: KAKEN

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Increased generation of reactive oxygen species (ROS) is recognized as a prominent feature of vascular dysfunction with diabetes. For self-monitoring of the risk of diabetic complications, we proposed a simple adhesion test of erythrocytes using positively charged surfaces and its adhesion property was found to correlate HbA(1c) level in diabetic patients. (C) 2011, The Society for Biotechnology, Japan. All rights reserved.

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