4.4 Article

Albumin production activity of primary rat hepatocytes is improved on type V collagen

Journal

JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 109, Issue 2, Pages 179-181

Publisher

SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/j.jbiosc.2009.07.017

Keywords

Hepatocyte; Type V collagen; Type I collagen; Monolayer culture; Albumin production

Funding

  1. Ministry of Education, Culture, Sports, Science and Technology of Japan [18360399]
  2. Grants-in-Aid for Scientific Research [18360399] Funding Source: KAKEN

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Primary rat hepatocytes were cultured on type V collagen. Hepatocyte spreading on type V collagen was inferior compared with that on type I collagen. However, the albumin production rates of hepatocytes cultured on type V collagen were approximately twice as high as those of hepatocytes cultured on type I collagen. (C) 2009, The Society for Biotechnology, Japan. All rights reserved.

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