Journal
JOURNAL OF BIOPHOTONICS
Volume 8, Issue 4, Pages 279-302Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.201400108
Keywords
optical coherence elastography; optical coherence tomography; tissue characterization; biomechanics; strain; natural frequency; Young's modulus; elastic wave
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Funding
- National Institute of Health [1R01EY022362, 1R01HL120140, U54HG006348]
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Optical coherence elastography (OCE) represents the frontier of optical elasticity imaging techniques and focuses on the micro-scale assessment of tissue biomechanics in 3D that is hard to achieve with traditional elastographic methods. Benefit from the advancement of optical coherence tomography, and driven by the increasing requirements in nondestructive biomechanical characterization, this emerging technique recently has experienced a rapid development. In this paper, we start with the description of the mechanical contrast that has been employed by OCE and review the state-of-the-art techniques based on the reported applications and discuss the current technical challenges, emphasizing the unique role of OCE in tissue mechanical characterization.
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