Journal
JOURNAL OF BIOPHOTONICS
Volume 6, Issue 1, Pages 20-35Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.201200133
Keywords
surface-enhanced Raman spectroscopy; Ag nanorod arrays; SERS; substrates; biosensing; bioanalytical; virus; bacteria; applications
Categories
Funding
- UGA Office of the Vice President for Research through a UGA Faculty of Infectious Disease Seed Grant
- U.S. Army Research Laboratory [W911NF-07-R-001-04]
- National Institutes of Health [GM102546]
Ask authors/readers for more resources
Recent progress in substrate nanofabrication has led to the development of Ag nanorod arrays as uniform, reproducible, large area SERS-active substrates with high signal enhancement. These novel nanostructures fabricated by oblique angle vapor deposition (OAD) offer a robust platform for the rapid detection of biological agents and open new perspectives for the development and integration of biomedical diagnostic for clinical and therapeutic applications. Ag nanorod arrays have been investigated as SERS-active substrates for the detection and identification of pathogens, including bacteria and viruses, as well as to evaluate the potential of this biosensing platform for bio-recognition of high affinity events using oligonucleotide-modified substrates. This review summarizes the various nanostructured substrates designed for SERS-based applications, highlights the nanofabrication methodology used to produce Ag nanorod arrays, outlines their morphological and physical properties, and provides a summary of the most recent uses of these substrates for clinical diagnostic and biomedical applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available