Journal
JOURNAL OF BIOPHOTONICS
Volume 5, Issue 1, Pages 40-46Publisher
WILEY-BLACKWELL
DOI: 10.1002/jbio.201100058
Keywords
phospholipid vesicles; microfluidic jetting; biological membranes; membrane composition; Raman scattering
Categories
Funding
- DFG through the Nanosystems Initiative Munich (NIM)
- ERC
Ask authors/readers for more resources
Microfluidic jetting is a promising method to produce giant unilamellar phospholipid vesicles for mimicking living cells in biomedical studies. We have investigated the chemical composition of membranes of vesicles prepared using this approach by means of Raman scattering spectroscopy. The membranes of all jetted vesicles are found to contain residuals of the organic solvent decane used in the preparation of the initial planar membrane. The decane inclusions are randomly distributed over the vesicle surface area and vary in thickness from a few to several tens of nanometers. Our findings point out that the membrane properties of jetted vesicles may differ considerably from those of vesicles prepared by other methods and from those of living cells. (C) 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available