Related references
Note: Only part of the references are listed.Transcriptional Activation of the cAMP-responsive Modulator Promoter in Human T Cells Is Regulated by Protein Phosphatase 2A-mediated Dephosphorylation of SP-1 and Reflects Disease Activity in Patients with Systemic Lupus Erythematosus
Yuang-Taung Juang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus
Jing Li et al.
MOLECULAR BIOLOGY REPORTS (2011)
Interleukin-6 promotes arthritis and joint deformation in patients with systemic lupus erythematosus
G. O. Eilertsen et al.
LUPUS (2011)
Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
Wei Liao et al.
NATURE IMMUNOLOGY (2011)
Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
Xiang-Ping Yang et al.
NATURE IMMUNOLOGY (2011)
Recovery of the immune balance between Th17 and regulatory T cells as a treatment for systemic lupus erythematosus
Ji Yang et al.
RHEUMATOLOGY (2011)
Glucocorticoids enhance Th17/Th1 imbalance and signal transducer and activator of transcription 3 expression in systemic lupus erythematosus patients
Catuxa Prado et al.
RHEUMATOLOGY (2011)
Expansion of Circulating T Cells Resembling Follicular Helper T Cells Is a Fixed Phenotype That Identifies a Subset of Severe Systemic Lupus Erythematosus
Nicholas Simpson et al.
ARTHRITIS AND RHEUMATISM (2010)
Tocilizumab in Systemic Lupus Erythematosus Data on Safety, Preliminary Efficacy, and Impact on Circulating Plasma Cells From an Open-Label Phase I Dosage-Escalation Study
Gabor G. Illei et al.
ARTHRITIS AND RHEUMATISM (2010)
Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis
Y. Wang et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
The imbalance between regulatory and IL-17-secreting CD4+ T cells in lupus patients
Jilin Ma et al.
CLINICAL RHEUMATOLOGY (2010)
Revisiting the role of IL-2 in autoimmunity
Hans Dooms et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Expansion of regulatory T cells via IL-2/anti-IL-2 mAb complexes suppresses experimental myasthenia
Ruolan Liu et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor
Fabienne Mackay et al.
IMMUNOLOGICAL REVIEWS (2010)
Anticytokine therapies in systemic lupus erythematosus
Antonio La Cava
IMMUNOTHERAPY (2010)
The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity
Linda A. Lieberman et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2010)
Interleukin 6 (IL-6) Deficiency Delays Lupus Nephritis in MRL-Fas(lpr) Mice: The IL-6 Pathway as a New Therapeutic Target in Treatment of Autoimmune Kidney Disease in Systemic Lupus Erythematosus
Hannes Cash et al.
JOURNAL OF RHEUMATOLOGY (2010)
The interferon-α signature of systemic lupus erythematosus
G. Obermoser et al.
LUPUS (2010)
Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus
Jens Y. Humrich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Proinflammatory T helper type 17 cells are effective B-cell helpers
Meike Mitsdoerffer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Effector and Regulatory T-cell Subsets in Autoimmunity and Tissue Inflammation
A. Jaeger et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2010)
Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus
Kamini Shah et al.
ARTHRITIS RESEARCH & THERAPY (2010)
Neutralization of Interferon-alpha/beta-Inducible Genes and Downstream Effect in a Phase I Trial of an Anti-Interferon-alpha Monoclonal Antibody in Systemic Lupus Erythematosus
Yihong Yao et al.
ARTHRITIS AND RHEUMATISM (2009)
A Polymorphism Within IL21R Confers Risk for Systemic Lupus Erythematosus
Ryan Webb et al.
ARTHRITIS AND RHEUMATISM (2009)
Th17 and Natural Treg Cell Population Dynamics in Systemic Lupus Erythematosus
Ji Yang et al.
ARTHRITIS AND RHEUMATISM (2009)
Evidence for the role of Th-17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody
Masahiko Mihara et al.
BIOFACTORS (2009)
Interleukin-17 and systemic lupus erythematosus: current concepts
A. Nalbandian et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2009)
IL-17 producing CD4+ T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice
Colin Edgerton et al.
CLINICAL IMMUNOLOGY (2009)
Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases
Xiaoyu Hu et al.
IMMUNITY (2009)
Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
Dipyaman Ganguly et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
Kylie E. Webster et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
The Role of IL-23/IL-17 Axis in Lupus Nephritis
Zheng Zhang et al.
JOURNAL OF IMMUNOLOGY (2009)
IL-17 Induces Monocyte Migration in Rheumatoid Arthritis
Shiva Shahrara et al.
JOURNAL OF IMMUNOLOGY (2009)
IL-21 Mediates Suppressive Effects via Its Induction of IL-10
Rosanne Spolski et al.
JOURNAL OF IMMUNOLOGY (2009)
Human TCR-αβ+ CD4- CD8- T Cells Can Derive from CD8+ T Cells and Display an Inflammatory Effector Phenotype
Jose C. Crispin et al.
JOURNAL OF IMMUNOLOGY (2009)
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
Vesela Gateva et al.
NATURE GENETICS (2009)
Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
Agnes Doreau et al.
NATURE IMMUNOLOGY (2009)
Mechanisms of Disease: Interleukin-17 and Type 17 Helper T Cells.
Pierre Miossec et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
Jason A. Bubier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Identification of IL-17-producing FOXP3+ regulatory T cells in humans
Kui Shin Voo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The gene expression of type 17 T-helper cell-related cytokines in the urinary sediment of patients with systemic lupus erythematosus
Bonnie Ching-Ha Kwan et al.
RHEUMATOLOGY (2009)
Dysregulation of germinal centres in autoimmune disease
Carola G. Vinuesa et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Interleukin-6 Blockade Suppresses Autoimmune Arthritis in Mice by the Inhibition of Inflammatory Th17 Responses
Minoru Fujimoto et al.
ARTHRITIS AND RHEUMATISM (2008)
Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients
Timothy B. Niewold et al.
ARTHRITIS AND RHEUMATISM (2008)
Th17/Treg in Human Graft-Versus-Host-Disease (GvHD) of the Gastro-Intestinal (GI) Tract
Gerard Socie et al.
BLOOD (2008)
Overexpression of interleukin-12 and T helper 1 predominance in lupus nephritis
M. Tucci et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2008)
Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity
Chun Kwok Wong et al.
CLINICAL IMMUNOLOGY (2008)
The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer
Rosanne Spolski et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history
Patricia Fitzgerald-Bocarsly et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2008)
IL-2 induces in vivo suppression by CD4+CD25+Foxp3+ regulatory T cells
Susan Brandenburg et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
A fundamental role for interleukin-21 in the generation of T follicular helper cells
Alexis Vogelzang et al.
IMMUNITY (2008)
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
Qizhi Tang et al.
IMMUNITY (2008)
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
Xuexian O. Yang et al.
IMMUNITY (2008)
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity
Jared M. Odegard et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
Matthias Lochner et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
被撤回的出版物: Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo (Retracted article. See vol. 184, pg. 6556, 2010)
Suresh Radhakrishnan et al.
JOURNAL OF IMMUNOLOGY (2008)
Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys
Jose C. Crispin et al.
JOURNAL OF IMMUNOLOGY (2008)
Isoform-specific inhibition of RORα-mediated transcriptional activation by human FOXP3
Jianguang Du et al.
JOURNAL OF IMMUNOLOGY (2008)
Interleukin 21: a cytokine/cytokine receptor system that has come of age
Warren J. Leonard et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
Liang Zhou et al.
NATURE (2008)
IL-21 and TGF-β are required for differentiation of human TH17 cells
Li Yang et al.
NATURE (2008)
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
John B. Harley et al.
NATURE GENETICS (2008)
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
Nicolas Manel et al.
NATURE IMMUNOLOGY (2008)
How interferon-gamma keeps autoimmune diseases in check
Hilde Kelchtermans et al.
TRENDS IN IMMUNOLOGY (2008)
Interleukin-21: a critical regulator of the balance between effector and regulatory T-cell responses
Giovanni Monteleone et al.
TRENDS IN IMMUNOLOGY (2008)
Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus
A. H. Sawalha et al.
ANNALS OF THE RHEUMATIC DISEASES (2008)
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
Hui-Chen Hsu et al.
NATURE IMMUNOLOGY (2008)
Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease
Tangsheng Yi et al.
BLOOD (2008)
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
Mandy J. McGeachy et al.
NATURE IMMUNOLOGY (2007)
Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration
Stefan Kuchen et al.
JOURNAL OF IMMUNOLOGY (2007)
Systemic lupus erythematosus:: new molecular targets
Jose C. Crispin et al.
ANNALS OF THE RHEUMATIC DISEASES (2007)
IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells
Shujuan Liu et al.
INTERNATIONAL IMMUNOLOGY (2007)
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
Liang Zhou et al.
NATURE IMMUNOLOGY (2007)
Phenotypic and functional features of human Th17 cells
Francesco Annunziato et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
Thomas Korn et al.
NATURE (2007)
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Roza Nurieva et al.
NATURE (2007)
Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells
Hee-Kap Kang et al.
JOURNAL OF IMMUNOLOGY (2007)
TH-17 cells in the circle of immunity and autoimmunity
Estelle Bettelli et al.
NATURE IMMUNOLOGY (2007)
IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression
Deborah Herber et al.
JOURNAL OF IMMUNOLOGY (2007)
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
Arian Laurence et al.
IMMUNITY (2007)
IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes
Ilaria Peluso et al.
JOURNAL OF IMMUNOLOGY (2007)
Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus
Bailin Liang et al.
IMMUNOLOGY (2006)
Cutting edge: Interleukin 17 signals through a heteromeric receptor complex
Dean Toy et al.
JOURNAL OF IMMUNOLOGY (2006)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli et al.
NATURE (2006)
Transforming growth factor-β induces development of the TH17 lineage
PR Mangan et al.
NATURE (2006)
T cell cytokine imbalance towards production of IFN-γ and IL-10 in NZB/W F1 lupus-prone mice is associated with autoantibody levels and nephritis
P. Enghard et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2006)
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
M Veldhoen et al.
IMMUNITY (2006)
Global natural regulatory T cell depletion in active systemic lupus erythematosus
M Miyara et al.
JOURNAL OF IMMUNOLOGY (2005)
Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity
Z Wu et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
H Park et al.
NATURE IMMUNOLOGY (2005)
Nucleic acids of mammalian origin can act as endogenous ligands for toll-like receptors and may promote systemic lupus erythematosus
FJ Barrat et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
CG Vinuesa et al.
NATURE (2005)
The therapy of autoimmune diseases by anti-interleukin-6 receptor antibody
M Mihara et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2005)
Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
R Setoguchi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
S Sigurdsson et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
Increase in activated CD8+T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus
P Blanco et al.
ARTHRITIS AND RHEUMATISM (2005)
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
CL Langrish et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Biology of IL-21 and the IL-21 receptor
DS Mehta et al.
IMMUNOLOGICAL REVIEWS (2004)
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
MW Boulé et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of blimp-1 and bcl-61
K Ozaki et al.
JOURNAL OF IMMUNOLOGY (2004)
Induction of interferon-a production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late anoptotic cells and lupus IgG
T Lövgren et al.
ARTHRITIS AND RHEUMATISM (2004)
Rationale for interleukin-6 blockade in systemic lupus erythematosus
E Tackey et al.
LUPUS (2004)
Interleukin-21 inhibits dendritic cell activation and maturation
K Brandt et al.
BLOOD (2003)
FcγRIIa is expressed on natural IFN-α-producing cells (plasmacytoid dendritic cells) and is required for the IFN-α production induced by apoptotic cells combined with lupus IgG
U Båve et al.
JOURNAL OF IMMUNOLOGY (2003)
Cytokine balance in kidney tissue from lupus nephritis patients
WS Uhm et al.
RHEUMATOLOGY (2003)
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
L Bennett et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
EC Baechler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Systemic lupus erythematosus and the type I interferon system
L Ronnblom et al.
ARTHRITIS RESEARCH & THERAPY (2003)
Antisense cyclic adenosine 5′-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus
K Tenbrock et al.
JOURNAL OF IMMUNOLOGY (2002)
Interferon-γ is required for lupus nephritis in mice treated with the hydrocarbon oil pristane
HB Richards et al.
KIDNEY INTERNATIONAL (2001)
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
N Kadowaki et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Plasmacytoid dendritic cells (natural interferon-α/β-producing cells) accumulate in cutaneous lupus erythematosus lesions
L Farkas et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
IL-17-induced cytokine release in human bronchial epithelial cells in vitro:: role of mitogen-activated protein (MAP) kinases
M Laan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Presence of cutaneous interferon-alpha producing cells in patients with systemic lupus erythematosus
S Blomberg et al.
LUPUS (2001)
IL-17 stimulates intraperitoneal neutrophil infiltration through the release of GROα chemokine from mesothelial cells
J Witowski et al.
JOURNAL OF IMMUNOLOGY (2000)
Increased excretions of β2-microglobulin, IL-6, and IL-8 and decreased excretion of Tamm-Horsfall glycoprotein in urine of patients with active lupus nephritis
CY Tsai et al.
NEPHRON (2000)
Treatment of murine lupus with cDNA encoding IFN-γR/Fc
BR Lawson et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis
P Schwarzenberger et al.
JOURNAL OF IMMUNOLOGY (2000)
Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus
CK Wong et al.
LUPUS (2000)
Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
AA Bengtsson et al.
LUPUS (2000)
Etiopathogenesis of systemic lupus erythematosus
M Herrmann et al.
IMMUNOLOGY TODAY (2000)
Share Paper
