Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 19, Issue 11, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.JBO.19.11.116005
Keywords
low coherence interferometry; fine-needle aspiration biopsy; tissue-type differentiation; breast cancer biopsy aiding capabilities
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We present portable preclinical low-coherence interference (LCI) instrumentation for aiding fine needle aspiration biopsies featuring the second-generation LCI-based biopsy probe and an improved scoring algorithm for tissue differentiation. Our instrument and algorithm were tested on 38 mice with cultured tumor mass and we show the specificity, sensitivity, and positive predictive value of tumor detection of over 0.89, 0.88, and 0.96, respectively. (C) The Authors. Published by SPIE
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