4.5 Article

Modeling of the temporal effects of heating during infrared neural stimulation

Journal

JOURNAL OF BIOMEDICAL OPTICS
Volume 18, Issue 3, Pages -

Publisher

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.JBO.18.3.035004

Keywords

optical stimulation; cochlear implant; Monte Carlo; simulations; laser; finite element analysis

Funding

  1. Australian Research Council [LP120100264]
  2. Australian Research Council [LP120100264] Funding Source: Australian Research Council

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A model of infrared neural stimulation (INS) has been developed to allow the temporal characteristics of different stimulation parameters and geometries to be better understood. The model uses a finite element approach to solve the heat equation and allow detailed analysis of heat during INS with both microsecond and millisecond laser pulses. When compared with experimental data, the model provides insight into the mechanisms behind INS. In particular, the analysis suggests that there may be two broad regimes of INS: the process tends to be limited by the total pulse energy for pulse lengths below 100 mu s, while the temperature gradient with respect to time becomes more important above 100 mu s. (C) 2013 Society of Photo-Optical Instrumentation Engineers (SPIE)

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