Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 15, Issue 1, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3285504
Keywords
laser speckle contrast; blood flow; biomedical imaging
Funding
- National Institutes of Health (NIH) [P50-NS010828, P01-NS055104, R01-NS057476]
- American Heart Association [0735136N]
- National Science Foundation [CBET/0737731]
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P50NS010828, R01NS057476, P01NS055104] Funding Source: NIH RePORTER
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First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3285504]
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