Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 15, Issue 3, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3431712
Keywords
quantitative phase contrast imaging; digital holographic microscopy; live cell imaging; mitosis; cell cycle; cell tracking
Funding
- German Federal Ministry of Education and Research (BMBF) [FKZ 13N9270]
- Deutsche Forschungsgemeinschaft (DFG) [KA 717/4-3]
- Graduiertenkolleg [GRK 1409]
- Interdisciplinary Center of Clinical Research (IZKF) Munster [Me2/023/08]
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Digital holographic microscopy (DHM) enables quantitative multifocus phase contrast imaging for nondestructive technical inspection and live cell analysis. Time-lapse investigations on human brain microvascular endothelial cells demonstrate the use of DHM for label-free dynamic quantitative monitoring of cell division of mother cells into daughter cells. Cytokinetic DHM analysis provides future applications in toxicology and cancer research. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3431712]
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