Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 15, Issue 4, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3479931
Keywords
optical coherence tomography; cancer; lymph node; parametric imaging; parametric optical coherence tomography
Funding
- National Breast Cancer Foundation (Australia)
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We present a parametric optical coherence tomography (OCT) technique to improve contrast between malignant and healthy non-neoplastic tissue. The technique incorporates a fully automated method to extract tissue attenuation characteristics. Results are represented visually as a parametric en face image, where the parameter used for contrast is indicative of the relative optical attenuation coefficient of the tissue. We present the first parametric OCT images of human lymph nodes containing malignant cells, and demonstrate improved tissue contrast over en face OCT images. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3479931]
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