Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 15, Issue 3, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3443793
Keywords
photoacoustic tomography; absorption spectroscopy; water content in tissue
Funding
- National Institutes of Health [R01 EB000712, EB000712A2S1, R01 EB00071207S2, R01 EB008085, R01 CA113453901, U54 CA136398, 5P60 DK02057933]
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Photoacoustic tomography (PAT) has been widely used to image optically absorptive objects in both human and animal tissues. For the first time, we present imaging of water with laser-based PAT. We photoacoustically measure the absorption spectra of water-ethanol mixtures at various water concentrations, and then image water-ethanol and pure-water inclusions in gel and a water inclusion in fat tissue. The significant difference in photoacoustic signals between water and fat tissue indicates that the laser-based PAT has the potential to detect water content in tissue. c 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3443793]
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