Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 14, Issue 3, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3147407
Keywords
thermoacoustic tomography; photoacoustic tomography; contrast agents; single-walled carbon nanotubes; carbon nanotubes
Funding
- National Institutes of Health [R01 EB000712, R01 NS46214, R01 EB008085, U54 CA136398]
- Office of the Vice President of Research at Stony Brook University
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We have developed a novel carbon nanotube-based contrast agent for both thermoacoustic and photoacoustic tomography. In comparison to deionized water, single-walled carbon nanotubes exhibited more than twofold signal enhancement for thermoacoustic tomography at 3 GHz. In comparison to blood, they exhibited more than sixfold signal enhancement for photoacoustic tomography at 1064 nm wavelength. The large contrast enhancement of single-walled carbon nanotubes was further corroborated by tissue phantom imaging studies. (C) 2009 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3147407]
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