Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 13, Issue 6, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3037340
Keywords
optical coherence tomography; endomicroscopy; balloon catheter; internal organ imaging
Funding
- National Institutes of Health [R21 CA116442, R01 CA120480]
- National Science Foundation
- Coulter Foundation Translational Research Awards
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We report on a new optics design for an optical coherence tomography (OCT) balloon imaging catheter. The design involves a miniature compound gradient-index (GRIN) rod lens, which consists of a fiber optic mode-field reducer and relay rod lenses to achieve predictable high lateral resolution at a desired large working distance. The compound lens design significantly simplifies the engineering process for an OCT catheter and enables 3-D full circumferential cross sectional imaging of large luminal organs such as human esophagus. An as-designed OCT catheter is developed and demonstrated for real-time in vivo swine esophagus imaging in a 3-D spiral fashion. (C) 2008 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3037340]
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