Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 13, Issue 2, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.2904965
Keywords
photoacoustics; microscopy; biomedical optics; photoacoustic; spectroscopy
Funding
- NIBIB NIH HHS [R01 EB000712] Funding Source: Medline
- NINDS NIH HHS [R01 NS46214, R01 NS046214] Funding Source: Medline
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We build a photoacoustic imaging system using an intensity-modulated continuous-wave laser source, which is an inexpensive, compact, and durable 120-mW laser diode. The goal is to significantly reduce the costs and sizes of photoacoustic imaging systems. By using a bowl-shaped piezoelectric transducer, whose numerical aperture is 0.85 and resonance frequency is 2.45 MHz, we image biological tissues with a lateral resolution of 0.45 mm, an axial resolution of 1 mm, and an SNR as high as 43 dB. (C) 2008 Society of Photo-Optical Instrumentation Engineers.
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