4.5 Review

Nanoparticle Based Tailoring of Adjuvant Function: The Role in Vaccine Development

Journal

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 10, Issue 9, Pages 2317-2331

Publisher

AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2014.1991

Keywords

Vaccine Delivery; Nanoparticles; Liposomes; Virosomes; Immunology

Funding

  1. Department of Biotechnology, Government of India [862/DEL/2014]

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Vaccination is one of the most powerful therapeutic tools for prevention and management of various infective and noninfective diseases including malignancy. Mass vaccination is a great strategy for eradicating major infectious diseases throughout the world like small pox. Application of nanotechnology for antigen delivery is a unique area of research and development which can change the vaccination strategy and policy in future. Nanocarriers can enhance antigen presentation including modulation of antigen processing pathways according to the specific need. The current review explores the pros and cons of application of different nanomaterials for antigen presentation and vaccine development.

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