4.5 Article

Safety Assessment of Nanoparticles Cytotoxicity and Genotoxicity of Metal Nanoparticles In Vitro

Journal

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 7, Issue 1, Pages 20-21

Publisher

AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2011.1180

Keywords

Nanoparticles; Nanomaterial Safety; Iron Oxide; DNA Damage; Comet Assay; Cytotoxicity; Genotoxicity

Funding

  1. EC [Health-2007-1.3-4, 201335]

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There is an urgent need to investigate the mechanisms of action of NMs and to develop testing strategies to assess potential environmental and human hazard. Our study has shown that metal nanoparticles such as iron oxide may induce genotoxic effect. It was inferred that coating and surface properties influence NPs cytotoxicity and genotoxicity.

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