Journal
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 5, Issue 2, Pages 172-181Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2009.1023
Keywords
Magnetic Nanoparticles; Hydrophilic Magnetite; Aminodextran; DNA; RNA; Diagnosis; Capture of Nucleic Acids; Amplification
Funding
- AMBRE [GenHomme 03 2 90 60 79]
Ask authors/readers for more resources
Within the framework of medical diagnosis, the main objective is the development of hydrophilic magnetic particles for the generic capture of the nucleic acids in order to enhance the sensitivity. The strategy used in this work is based on the synthesis of cationic and hydrophilic magnetic nanoparticles bearing aminodextran. The synthesis was performed using two different processes: (i) coprecipitation of the ferrous and ferric salts in the presence of an aqueous solution of aminodextran and (ii) via adsorption of aminodextran on iron oxide nanoparticles. The obtained particles are characterized and evaluated in non-specific nucleic acids extraction and amplification.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available