Journal
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
Volume 88B, Issue 1, Pages 75-82Publisher
WILEY
DOI: 10.1002/jbm.b.31153
Keywords
atomic force microscopy; contact lens; degradation; surface characterization; wear
Funding
- Science and Technology Foundation (FCT) - Ministry of Science and Superior Education (MCES) (European Social Funding) [8281/2002]
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Purpose. To evaluate the qualitative and quantitative topographic changes in the surface of worn contact lenses (CLs) of different materials using atomic force microscopy (AFM). Methods. The topography of five different CL materials was evaluated with AFM over a surface of 25 mu m(2) according to previously published experimental setup. Average roughness (R-a) and root mean square (Rms) values were obtained for unworn and worn samples. Results. The R-a, value increased for balafilcon A (11.62-13.68 nm for unworn and worn samples, respectively), lotrafilcon A (3.67-15.01 nm for unworn and worn samples, respectively), lotrafilcon B (4.08-8.42 nm for unworn and worn samples, respectively), galyfilcon A (2.81-14.6 nm for unworn and worn samples, respectively), and comfilcon A (2.87-4.63 mu for unworn and worn samples, respectively). Differences were statistically significant for all lenses except Rms and R-a for comfilcon A, and R-a parameter for balafilcon A (p > 0.05). The least relative increase was observed for some balarilcon A samples and for some of these samples the roughness decreased after the lenses had been worn. Conclusion. The changes in surface roughness between unworn and worn lenses are different for different silicone-hydrogel materials. Overall all CLs increased the degree of surface roughness after being worn, even for very short periods of time. However, for samples of balafilcon A, roughness increases at a lower extent or even can decrease as compared to unworn samples of the same material due to filling of the macropores. (c) 2008 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 88B: 75-82, 2009
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