Journal
NEPHROLOGY DIALYSIS TRANSPLANTATION
Volume 31, Issue 3, Pages 375-382Publisher
OXFORD UNIV PRESS
DOI: 10.1093/ndt/gfv005
Keywords
inflammatory bowel disease; kidney stones; oxalate; transplantation; urolithiasis
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Funding
- Rare Kidney Stone Consortium part of the National Center for Advancing Translational Sciences (NCATS) Rare Diseases Clinical Research Network (RDCRN) [U54KD083908, DK83908]
- NCATS
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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Hyperoxaluria is a frequent complication of inflammatory bowel diseases, ileal resection and Roux-en-Y gastric bypass and is well-known to cause nephrolithiasis and nephrocalcinosis. The associated prevalence of chronic kidney disease and end-stage kidney disease (ESKD) is less clear but may be more consequential than recognized. In this review, we highlight three cases of ESKD due to enteric hyperoxaluria following small bowel resections. We review current information on the pathophysiology, complications and treatment of this complex disease.
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