Journal
JOURNAL OF BIOMEDICAL INFORMATICS
Volume 46, Issue 5, Pages 774-781Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jbi.2013.07.001
Keywords
Cloud computing; Bioinformatics; Big data; Genomics; Hadoop
Funding
- Embark Initiative by an Irish Research Council (IRC) [RS/2012/122]
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Since the completion of the Human Genome project at the turn of the Century, there has been an unprecedented proliferation of genomic sequence data. A consequence of this is that the medical discoveries of the future will largely depend on our ability to process and analyse large genomic data sets, which continue to expand as the cost of sequencing decreases. Herein, we provide an overview of cloud computing and big data technologies, and discuss how such expertise can be used to deal with biology's big data sets. In particular, big data technologies such as the Apache Hadoop project, which provides distributed and parallelised data processing and analysis of petabyte (PB) scale data sets will be discussed, together with an overview of the current usage of Hadoop within the bioinformatics community. (C) 2013 Elsevier Inc. All rights reserved.
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