4.5 Article

The MPEG Monophosphate Ester: Synthesis and Characterization

Journal

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
Volume 20, Issue 14, Pages 2103-2116

Publisher

VSP BV
DOI: 10.1163/156856208X400483

Keywords

Poly(ethylene glycol); phosphorylation; phosphoric acid; pyrophosphoric acid; polyphosphoric acid

Funding

  1. Polish State Committee [T09A 055 29]

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Methods of preparation of the phosphoric ester of monomethyl ether of poly(ethylene glycol) (MPEG-P) from MPEG (M(n) = 550 and 2000) and phosphoric acid (P), or its derivatives - pyrophosphoric acid (PY), polyphosphoric acid (PP) and POCl(3)- are described and compared. MPEG-P was isolated in a pure state (no detectable impurities) and characterized. (C) Koninklijke Brill NV, Leiden, 2009

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