Journal
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
Volume 19, Issue 8, Pages 989-1005Publisher
VSP BV
DOI: 10.1163/156856208784909327
Keywords
wound healing; animal models; mouse; transgenic; knockout
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Transgenic and knockout mouse technology represents a powerful tool for exploring the molecular pathways behind the wound healing process. The design and utilization of mouse wound healing models must be approached mindful of limitations of both the transgenic technology and the models themselves in order to continue generating useful information from studies with transgenic mice. A battery of standard and impaired wound healing models, when used in a systematic and combinatorial fashion, should yield significant contributions to wound healing research.
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