Journal
JOURNAL OF BIOLOGICAL RHYTHMS
Volume 25, Issue 5, Pages 381-384Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0748730410379080
Keywords
circadian; human; relative coordination; blindness; entrainment; melatonin
Categories
Funding
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [R01HD042125] Funding Source: NIH RePORTER
- NATIONAL CENTER FOR RESEARCH RESOURCES [K01RR024120, K23RR017636, M01RR000334] Funding Source: NIH RePORTER
- NATIONAL EYE INSTITUTE [R01EY018312] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [R01AG021826] Funding Source: NIH RePORTER
- NCRR NIH HHS [M01 RR000334, K23RR017636, UL1 RR024120] Funding Source: Medline
- NEI NIH HHS [R01 EY018312-09A1] Funding Source: Medline
- NIA NIH HHS [R01 AG21826] Funding Source: Medline
- NICHD NIH HHS [R01 HD42125] Funding Source: Medline
Ask authors/readers for more resources
In the absence of the entraining light-dark cycle, most totally blind humans free-run, albeit with relative coordination to nonphotic zeitgebers. Such blind free-runners (BFRs) often attempt to maintain a 24-h sleep-wake schedule and consequently suffer from recurrent sleep disruption and daytime somnolence. This study was conducted to determine the periods of the free-running melatonin rhythm and of the rest-activity cycle in 16 BFRs. It was found that the non-24-h component of the rest-activity rhythm correlated with the observed period of the circadian pacemaker.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
