Journal
JOURNAL OF BIOLOGICAL PHYSICS
Volume 37, Issue 2, Pages 227-238Publisher
SPRINGER
DOI: 10.1007/s10867-010-9211-7
Keywords
DNA elasticity; DNA electrostatics; Buckling instability; DNA supercoiling
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Funding
- DFG
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We study the deformations of charged elastic rods under applied end forces and torques. For neutral filaments, we analyze the energetics of initial helical deformations and loop formation. We supplement this elastic approach with electrostatic energies of bent filaments and find critical conditions for buckling depending on the ionic strength of the solution. We also study force-induced loop opening, for parameters relevant for DNA. Finally, some applications of this nano-mechanical DNA model to salt-dependent onset of the DNA supercoiling are discussed.
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