4.0 Article

Dynamics of a minimal neural model consisting of an astrocyte, a neuron, and an interneuron

Journal

JOURNAL OF BIOLOGICAL PHYSICS
Volume 35, Issue 4, Pages 361-382

Publisher

SPRINGER
DOI: 10.1007/s10867-009-9143-2

Keywords

Neuron; Interneuron; Astrocyte; Receptors; Glutamate; ATP; Calcium

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In this paper, a biophysical neural network model consisting of a pyramidal neuron, an interneuron, and the astrocyte is studied. The corresponding dynamical properties are mainly investigated by using numerical simulations. The results show that the presence of the adenosine triphosphate and of the interneuron impacts the overall neural activity. It is shown that the fluxes of calcium through the cellular membrane strongly affect the modulation of the neural activity arising from the astrocyte.

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