4.4 Article

Substitution of aspartic acid with glutamic acid at position 67 of the BRCA1 RING domain retains ubiquitin ligase activity and zinc(II) binding with a reduced transition temperature

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Cisplatin Affects the Conformation of Apo Form, not Holo Form, of BRCA1 RING Finger Domain and Confers Thermal Stability

Apichart Atipairin et al.

CHEMISTRY & BIODIVERSITY (2010)

Article Biochemistry & Molecular Biology

Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1

Eva Dizin et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

BRCA1/BARD1 E3 Ubiquitin Ligase Can Modify Histones H2A and H2B in the Nucleosome Particle

Amit Thakar et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2010)

Article Biochemistry & Molecular Biology

The UBXN1 Protein Associates with Autoubiquitinated Forms of the BRCA1 Tumor Suppressor and Inhibits Its Enzymatic Function

Foon Wu-Baer et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

Review Cell Biology

BRCA1 and its toolbox for the maintenance of genome integrity

Michael S. Y. Huen et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Editorial Material Medicine, General & Internal

Traffic Control for BRCA1

William D. Foulkes

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Biochemistry & Molecular Biology

Functional Analysis of Familial Asp67Glu and Thr1051Ser BRCA1 Mutations in Breast/Ovarian Carcinogenesis

Malinee Pongsavee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)

Review Biochemistry & Molecular Biology

Discovery of Cellular Regulation by Protein Degradation

Alexander Varshavsky

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Cell Biology

The ubiquitin E3 ligase activity of BRCA1 and its biological functions

Wenwen Wu et al.

Cell Division (2008)

Article Oncology

Oncogenic BARD1 isoforms expressed in gynecological cancers

Lin Li et al.

CANCER RESEARCH (2007)

Article Biochemistry & Molecular Biology

Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells

K. Kehn et al.

ONCOGENE (2007)

Article Multidisciplinary Sciences

A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase

Andrew A. Horwitz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Estrogen receptor α is a putative substrate for the BRCA1 ubiquitin ligase

Catherine M. Eakin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Oncology

BRCA1 ubiquitinates RPB8 in response to DNA damage

Wenwen Wu et al.

CANCER RESEARCH (2007)

Review Biochemistry & Molecular Biology

Sticky fingers: zinc-fingers as protein-recognition motifs

Roland Gamsjaeger et al.

TRENDS IN BIOCHEMICAL SCIENCES (2007)

Review Biochemistry & Molecular Biology

The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability

K. Gudmundsdottir et al.

ONCOGENE (2006)

Article Biochemistry & Molecular Biology

A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination

PS Brzovic et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility

JR Morris et al.

HUMAN MOLECULAR GENETICS (2006)

Article Biochemical Research Methods

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

K Arnold et al.

BIOINFORMATICS (2006)

Article Biochemical Research Methods

Using circular dichroism spectra to estimate protein secondary structure

Norma J. Greenfield

NATURE PROTOCOLS (2006)

Article Biochemistry & Molecular Biology

BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II

LM Starita et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Regulation of BRICA1, BRCA2 and BARD1 intracellular trafficking

BR Henderson

BIOESSAYS (2005)

Article Biochemistry & Molecular Biology

Mass spectrometric and mutational analyses reveal lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase

H Nishikawa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

Binding and recognition in the assembly of an active BRCA1 /BARD1 ubiquitin-ligase complex

PS Brzovic et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

Y Xia et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

DL Mallery et al.

EMBO JOURNAL (2002)

Article Biochemistry & Molecular Biology

Autoubiquitination of the BRCA1-BARD1 RING ubiquitin ligase

A Chen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

BRCA1 RING domain cancer-predisposing mutations - Structural consequences and effects on protein-protein interactions

PS Brzovic et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

PS Brzovic et al.

NATURE STRUCTURAL BIOLOGY (2001)

Article Biochemistry & Molecular Biology

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

R Hashizume et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Multidisciplinary Sciences

Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

H Ruffner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)