Related references
Note: Only part of the references are listed.Visualization and Quantification of APP Intracellular Domain-Mediated Nuclear Signaling by Bimolecular Fluorescence Complementation
Florian Riese et al.
PLOS ONE (2013)
Turnover of Amyloid Precursor Protein Family Members Determines Their Nuclear Signaling Capability
Manuel T. Gersbacher et al.
PLOS ONE (2013)
Promiscuous Alzheimer's Amyloid: Yet Another Partner
Iryna Benilova et al.
SCIENCE (2013)
Novel APP/Aß mutation K16N produces highly toxic heteromeric Aß oligomers
Daniela Kaden et al.
EMBO MOLECULAR MEDICINE (2012)
Differential Regulation of Amyloid-β Endocytic Trafficking and Lysosomal Degradation by Apolipoprotein E Isoforms
Jie Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
Najla Kfoury et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The physiology of the beta-amyloid precursor protein intracellular domain AICD
Raphaelle Pardossi-Piquard et al.
JOURNAL OF NEUROCHEMISTRY (2012)
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
Iryna Benilova et al.
NATURE NEUROSCIENCE (2012)
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions
Jan Stoehr et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication
Ulrike K. Resenberger et al.
EMBO JOURNAL (2011)
Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis
Jason A. Bailey et al.
GENE (2011)
The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: Characterizing a new regulatory motif
Bryan Maloney et al.
GENE (2011)
Nuclear Tau, a Key Player in Neuronal DNA Protection
Audrey Sultan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Intraneuronal Amyloid β Oligomers Cause Cell Death Via Endoplasmic Reticulum Stress, Endosomal/Lysosomal Leakage, and Mitochondrial Dysfunction In Vivo
Tomohiro Umeda et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
APP processing in Alzheimer's disease
Yun-Wu Zhang et al.
MOLECULAR BRAIN (2011)
Novel Research Horizons for Presenilins and gamma-Secretases in Cell Biology and Disease
Bart De Strooper et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 26 (2010)
Immunohistochemical Visualization of Amyloid-beta Protein Precursor and Amyloid-beta in Extra- and Intracellular Compartments in the Human Brain
Leena Aho et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Aberrant Amyloid Precursor Protein (APP) Processing in Hereditary Forms of Alzheimer Disease Caused by APP Familial Alzheimer Disease Mutations Can Be Rescued by Mutations in the APP GxxxG Motif
Lisa-Marie Munter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Characterisation of the passive permeability barrier of nuclear pore complexes
Dagmar Mohr et al.
EMBO JOURNAL (2009)
Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer
Rakez Kayed et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Propagation of Tau Misfolding from the Outside to the Inside of a Cell
Bess Frost et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2
Daniela Kaden et al.
JOURNAL OF CELL SCIENCE (2009)
Aβ43 is more frequent than Aβ40 in amyloid plaque cores from Alzheimer disease brains
Hedvig Welander et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Role of Amyloid-β Glycine 33 in Oligomerization, Toxicity, and Neuronal Plasticity
Anja Harmeier et al.
JOURNAL OF NEUROSCIENCE (2009)
Microglia Mediate the Clearance of Soluble Aβ through Fluid Phase Macropinocytosis
Shweta Mandrekar et al.
JOURNAL OF NEUROSCIENCE (2009)
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers
Juha Lauren et al.
NATURE (2009)
The Role of Apolipoprotein E in Alzheimer's Disease
Jungsu Kim et al.
NEURON (2009)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Phorbol Ester Enhances KAI1 Transcription by Recruiting Tip60/Pontin Complexes
Alexandra Rowe et al.
NEOPLASIA (2008)
Internalization of β-amyloid peptide by primary neurons in the absence of apolipoprotein E
Lucila Saavedra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Amyloid precursor protein regulates brain apolipoprotein e and cholesterol metabolism through lipoprotein receptor LRP1
Qiang Liu et al.
NEURON (2007)
Differential regulation of basic helix-loop-helix factors Mash1 and Olig2 by β-amyloid accelerates both differentiation and death of cultured neural stem/progenitor cells
Yoko Uchida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Pore-forming proteins share structural and functional homology with amyloid oligomers
Yuji Yoshiike et al.
NEUROMOLECULAR MEDICINE (2007)
Intraneuronal A beta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration
Jerzy Wegiel et al.
ACTA NEUROPATHOLOGICA (2007)
Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
Rebecca Radde et al.
EMBO REPORTS (2006)
A dynamic relationship between intracellular and extracellular pools of A beta
S Oddo et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
3D structure of Alzheimer's amyloid-β(1-42) fibrils
T Lührs et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mitochondrial Aβ:: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
C Caspersen et al.
FASEB JOURNAL (2005)
Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes
JH Kim et al.
NATURE (2005)
Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease
Y Ohyagi et al.
FASEB JOURNAL (2005)
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
RC von Rotz et al.
JOURNAL OF CELL SCIENCE (2004)
Dissection of amyloid-β precursor protein-dependent transcriptional transactivation
XW Cao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Intracellular Aβ42 activates p53 promoter:: a pathway to neurodegeneration in Alzheimer's disease
Y Ohyagi et al.
FASEB JOURNAL (2004)
Amyloid β-peptide interactions with neuronal and glial cell plasma membrane:: Binding sites and implications for Alzheimer's disease
Y Verdier et al.
JOURNAL OF PEPTIDE SCIENCE (2004)
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
R Kayed et al.
SCIENCE (2003)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-κB and β-amyloid precursor protein
SH Baek et al.
CELL (2002)
The channel hypothesis of Alzheimer's disease: current status
BL Kagan et al.
PEPTIDES (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Selective cytotoxicity of intracellular amyloid β peptide1-42 through p53 and Bax in cultured primary human neurons
Y Zhang et al.
JOURNAL OF CELL BIOLOGY (2002)
A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60
XW Cao et al.
SCIENCE (2001)
Intraneuronal A beta 42 accumulation in human brain
GK Gouras et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)