4.6 Article

Use of Chimeras, Point Mutants, and Molecular Modeling to Map the Antagonist-binding Site of 4,4′,4,4′′′-(Carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic Acid (NF449) at P2X1 Receptors for ATP

Related references

Note: Only part of the references are listed.
Review Neurosciences

Exploring the ATP-binding site of P2X receptors

Thierry Chataigneau et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2013)

Review Biochemistry & Molecular Biology

Purinergic signalling: Its unpopular beginning, its acceptance and its exciting future

Geoffrey Burnstock

BIOESSAYS (2012)

Article Multidisciplinary Sciences

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Motoyuki Hattori et al.

NATURE (2012)

Article Multidisciplinary Sciences

Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel

Jonathan A. Roberts et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Biochemistry & Molecular Biology

Molecular and functional properties of P2X receptors-recent progress and persisting challenges

Karina Kaczmarek-Hajek et al.

PURINERGIC SIGNALLING (2012)

Article Biochemistry & Molecular Biology

The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels

Rebecca C. Allsopp et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Pharmacology & Pharmacy

Structural interpretation of P2X receptor mutagenesis studies on drug action

Richard J. Evans

BRITISH JOURNAL OF PHARMACOLOGY (2010)

Review Biochemistry & Molecular Biology

P2X receptors: dawn of the post-structure era

Mark T. Young

TRENDS IN BIOCHEMICAL SCIENCES (2010)

Review Pharmacology & Pharmacy

New structure enlivens interest in P2X receptors

Liam E. Browne et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Review Physiology

Signaling at Purinergic P2X Receptors

Annmarie Surprenant et al.

ANNUAL REVIEW OF PHYSIOLOGY (2009)

Article Multidisciplinary Sciences

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

Toshimitsu Kawate et al.

NATURE (2009)

Review Neurosciences

ATP-gated P2X cation-channels

Michael F. Jarvis et al.

NEUROPHARMACOLOGY (2009)

Article Biochemistry & Molecular Biology

Ectodomain Lysines and Suramin Block of P2X1 Receptors

Joan A. Sim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Neurosciences

Regulation of the desensitization and ion selectivity of ATP-gated P2X2 channels by phosphoinositides

Yuichiro Fujiwara et al.

JOURNAL OF PHYSIOLOGY-LONDON (2006)

Review Chemistry, Multidisciplinary

The Amber biomolecular simulation programs

DA Case et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)

Article Immunology

A role of the fast ATP-gated P2X, cation channel in thrombosis of small arteries in vivo

B Hechler et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2003)

Article Pharmacology & Pharmacy

NF449, a novel picomolar potency antagonist at human P2X1 receptors

M Hülsmann et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2003)

Article Biochemistry & Molecular Biology

Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor

SJ Royle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Pharmacology & Pharmacy

NF449:: a subnanomolar potency antagonist at recombinant rat P2X1 receptors

K Braun et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2001)

Article Biochemistry & Molecular Biology

The role of positively charged amino acids in ATP recognition by human P2X1 receptors

S Ennion et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)