Related references
Note: Only part of the references are listed.Dihydroartemisinin induces autophagy by suppressing NF-κB activation
Wei Hu et al.
CANCER LETTERS (2014)
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Joseph D. Mancias et al.
NATURE (2014)
Artemisinins: Pharmacological actions beyond anti-malarial
Wanxing Eugene Ho et al.
PHARMACOLOGY & THERAPEUTICS (2014)
Artemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo
Judong Luo et al.
RADIATION ONCOLOGY (2014)
At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy
Han-Ming Shen et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Lysosomal Iron, Iron Chelation, and Cell Death
Alexei Terman et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin
Xiao-Xue Du et al.
BIOMEDICINE & PHARMACOTHERAPY (2013)
Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
Jing Zhou et al.
CELL RESEARCH (2013)
Development of artemisinin compounds for cancer treatment
Henry C. Lai et al.
INVESTIGATIONAL NEW DRUGS (2013)
Mitoferrin-2-dependent Mitochondrial Iron Uptake Sensitizes Human Head and Neck Squamous Carcinoma Cells to Photodynamic Therapy
Hsin-I Hung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
Carmine Settembre et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
The Artemisinin Derivative Artesunate Inhibits Corneal Neovascularization by Inducing ROS-Dependent Apoptosis in Vascular Endothelial Cells
Rui Cheng et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)
Iron and cancer: more ore to be mined
Suzy V. Torti et al.
NATURE REVIEWS CANCER (2013)
Lysosomal Acidification Mechanisms
Joseph A. Mindell
ANNUAL REVIEW OF PHYSIOLOGY, VOL 74 (2012)
Mechanisms of Mammalian Iron Homeostasis
Kostas Pantopoulos et al.
BIOCHEMISTRY (2012)
Anti-malarial drug artesunate ameliorates oxidative lung damage in experimental allergic asthma
Wanxing Eugene Ho et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells
Chenjuan Zhou et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
Lysosomal Signaling Enhances Mitochondria-Mediated Photodynamic Therapy in A431 Cancer Cells: Role of Iron
Shalini Saggu et al.
PHOTOCHEMISTRY AND PHOTOBIOLOGY (2012)
Dihydroartemisinin induces autophagy and inhibits the growth of iron-loaded human myeloid leukemia K562 cells via ROS toxicity
Zeng Wang et al.
FEBS OPEN BIO (2012)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase
Yanyan Zhao et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2011)
The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials
Amy E. Mercer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
Anne Hamacher-Brady et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells
Takeshi Asano et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Lysosomal positioning coordinates cellular nutrient responses
Viktor I. Korolchuk et al.
NATURE CELL BIOLOGY (2011)
mTOR: from growth signal integration to cancer, diabetes and ageing
Roberto Zoncu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway
Chang Cheng et al.
PLOS ONE (2011)
Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo
Ji-Hui Du et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2010)
First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases
Suhail Ahmed Kabeer Rasheed et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
The yeast lysosome-like vacuole: Endpoint and crossroads
Sheena Claire Li et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Specific iron chelators determine the route of ferritin degradation
Ivana De Domenico et al.
BLOOD (2009)
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
Paul Saftig et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target
Shiming Zhang et al.
PLOS ONE (2009)
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello et al.
SCIENCE (2009)
Structure and regulation of the vacuolar ATPases
Daniel J. Cipriano et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)
Experimental therapy of hepatoma with artemisinin and its derivatives:: In vitro and in vivo activity, chemosensitization, and mechanisms of action
Junmei Hou et al.
CLINICAL CANCER RESEARCH (2008)
Translocation of Iron from Lysosomes into Mitochondria Is a Key Event During Oxidative Stress-Induced Hepatocellular Injury
Akira Uchiyama et al.
HEPATOLOGY (2008)
In situ detection of phosphorylated platelet-derived growth factor receptor β using a generalized proximity ligation method
Malin Jarvius et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells
Thomas Efferth et al.
PLOS ONE (2007)
Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion
Hitoshi Nakatogawa et al.
CELL (2007)
Simple quantitative detection of mitochondrial superoxide production in live cells
Partha Mukhopadhyay et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Evidence for the involvement of carbon-centered radicals in the induction of apoptotic cell death by artemisinin compounds
Amy E. Mercer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs
Paul A. Stocks et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Release of iron from ferritin requires lysosomal activity
Theodros Z. Kidane et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
The role of iron regulatory proteins in mammalian iron homeostasis and disease
Tracey A. Rouault
NATURE CHEMICAL BIOLOGY (2006)
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
M Komatsu et al.
JOURNAL OF CELL BIOLOGY (2005)
Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage
T Kurz et al.
BIOCHEMICAL JOURNAL (2004)
Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate
R Dell'Eva et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes
MA Aon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitochondrial formation of reactive oxygen species
JF Turrens
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR
HB Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro
HH Chen et al.
PHARMACOLOGICAL RESEARCH (2003)
Artemisinins target the SERCA of Plasmodium falciparum
U Eckstein-Ludwig et al.
NATURE (2003)
At the acidic edge: emerging functions for lysosomal membrane proteins
EL Eskelinen et al.
TRENDS IN CELL BIOLOGY (2003)
The vacuolar (H+)-atpases -: Nature's most versatile proton pumps
T Nishi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
Overexpression of wild type and mutated human ferritin H-chain in HeLa cells -: In vivo role of ferritin ferroxidase activity
A Cozzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)